PROLONGED HYPERPLASMINEMIA WITH MITOMYCIN C IN RABBITS
نویسندگان
چکیده
منابع مشابه
P 190 Corneal endothelial toxicity of mitomycin C in rabbits
Hsldw S.A.1, Buh~r~~nly J.1, Haswll P.D.1, Bowbr I.C.J.W.2, Bmn A.J.1 1 Depatlmenl of Ophthalmology, University ot Oxford. 2 Department of Bacterioboy. Oxford Regional FMii Heaith Laboratory. Purpose: lntravitreal antibiotic is the mainstay of endophthalmitis treatment. Repeat injections should be based on the knowledege of tissue levels. The purpose of this study is to assess the value of aque...
متن کاملOcular tissue concentrations of mitomycin C with variable dose and duration of application time in rabbits.
We measured mitomycin C (MMC) concentrations in ocular tissues in rabbits with variable dose (0.1, 0.2, or 0.4 mg) and duration of application time (1, 3, or 5 minutes) of MMC using high-performance liquid chromatography. Mitomycin C concentrations at the administered site after single subconjunctival application of MMC and after irrigation showed significant correlation with dose and duration ...
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Dorzolamide ophthalmic drop is one of the most common glaucoma medications but it has a short residence time in the eye. The aim of this study is to develop ocular dorzolamide HCl nanoliposomes (DRZ – nanoliposomes) and to evaluate their potential use for the treatment of ocular hypertension. Nanoliposomes were prepared using Reverse-phase evaporation vesicle (REV) and thin layer hydration (TLH...
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PURPOSE To determine a way to prevent the formation of adhesions and delay the time of suture adjustment in the course of adjustable strabismus surgery, an animal study was performed to assess and compare the effects of mitomycin C (Mit-C) and viscoelastic material Viscoat (sodium hyaluronate 3% and chondroitin sulphate 4%, Alcon, Fort Worth, TX). METHODS Right eyes of 47 rabbits were divided...
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Disposition characteristics of the macromolecular prodrug of mitomycin C (MMC), mitomycin C-dextran conjugate (MMC-D), in normal and tumor (VX2 carcinoma)-bearing rabbit thigh muscles were studied using the in situ vascular perfusion technique. Three types of cationic MMC-D (MMC-Dcat) and two types of anionic MMC-D (MMC-Dan) with different carrier molecular weights were used. After bolus arteri...
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ژورنال
عنوان ژورنال: The Keio Journal of Medicine
سال: 1964
ISSN: 1880-1293,0022-9717
DOI: 10.2302/kjm.13.165